Soursop Leaf
Annona muricata
Central America, South America, Caribbean
Traditional Uses
Traditionally used for fever, diabetes, hypertension, cough, digestive disorders, skin conditions, sleep support and infections.
Modern Research Uses
Leaf extracts studied for anticancer activity, anti-inflammatory effects, blood-pressure and blood-sugar lowering, antimicrobial activity and antioxidant properties.
Mechanism of Action
Annonaceous acetogenins inhibit mitochondrial complex I, reducing ATP production in tumour cells; flavonoids contribute antioxidant and anti-inflammatory effects.
Body Systems Affected
Prep & Administration
Toxicity Notes
Nervous, Digestive, Cardiovascular, Endocrine, Immune
Tea, Tincture, Capsules, Decoction, Poultice
Moderate
Prolonged excessive consumption may contribute to neurotoxicity due to annonacin; avoid long-term high-dose use.