Semicontra Bush
Dysphania ambrosioides
Central America, South America, Caribbean
Traditional Uses
Deworming and digestive, fever, cough and chest
Modern Research Uses
Leaf infusions studied as an anthelmintic to expel intestinal worms; extracts researched for antiparasitic activity against leishmania and trypanosomes; studied for immune-boosting and anti-inflammatory effects in infection models; essential oil noted for potent but toxic antiparasitic use
Mechanism of Action
Main compound is ascaridole. Iron activates it to release free radicals that damage parasites, which is also what makes it toxic in large amounts.
Body Systems Affected
Prep & Administration
Toxicity Notes
Digestive, Nervous, Cardiovascular, Immune
Tea, Tincture, Capsule, Topical oil, Poultice, Decoction
High
Can be fatal to humans in overdoses due to the compound ascaridole (shown in past events)